The Renoprotective Effects of Sodium Valproate as a Histone Deacetylase Inhibitor on Diabetic Nephropathy
نویسندگان
چکیده
J Babol Univ Med Sci; 19(9); Sep 2017; PP: 45-53 Received: Mar 23 2017, Revised: May 1
منابع مشابه
Valproate attenuates diabetic nephropathy through inhibition of endoplasmic reticulum stress-induced apoptosis
Previous studies have suggested that endoplasmic reticulum stress (ERS) is one of the mechanisms responsible for the pathogenesis of diabetic nephropathy (DN). Histone acetylation modification can regulate the transcription of genes and is involved in the regulation of ERS. Valproate (VPA), a nonselective histone deacetylase inhibitor, has been reported to have a protective role in kidney tissu...
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